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The following information is a summary. It is not intended to replace a doctor's instructions. Brand Name: Vicoprofen Generic Name: Hydrocodone and Ibuprofen Uses Hydrocodone (related to codeine) is in a class of drugs called narcotic analgesics. It is a pain reliever. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It relieves pain and decreases inflammation. Hydrocodone and ibuprofen are used together for the short-term treatment of pain. Hydrocodone and ibuprofen may also be used for purposes other than those listed in this medication guide. How to Take This Medication Take Vicoprofen exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Hydrocodone and ibuprofen can be taken with food or milk to decrease stomach upset. Never take more Vicoprofen than is prescribed for you. If your pain is not being adequately treated, talk to your doctor. Hydrocodone and ibuprofen may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in your diet may also help to alleviate constipation. Precautions Use caution when driving, operating machinery, or performing other hazardous activities. Hydrocodone and ibuprofen may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities. Do not drink alcohol while taking Vicoprofen. Alcohol may increase drowsiness or dizziness. Alcohol may also increase the risk of stomach bleeding while taking this medication. Do not take other prescription or over-the-counter medications that contain ibuprofen (Motrin, Advil, others) while taking Vicoprofen without first talking to your doctor. Drowsiness or dizziness caused by Vicoprofen may be increased by the effects of other drugs that cause drowsiness including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, muscle relaxants, and many others. Tell your doctor about all medicines that you are taking and do not take any medicine without first talking to your doctor. Possible Side Effects If you experience any of the following serious side effects, stop taking Vicoprofen and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); slow or weak breathing; yellowing of the skin or eyes; unusual fatigue, bleeding, or bruising; abdominal cramping, indigestion, or heartburn; black, bloody, or tarry stools; bloody vomit; decreased hearing or ringing in the ears; blurred vision or other visual problems; or sudden weight gain (fluid retention). Other, less serious side effects may be more likely to occur. Continue to take Vicoprofen and talk to your doctor if you experience constipation; dry mouth, nausea, or decreased appetite; dizziness, tiredness, or lightheadedness; muscle twitches; sweating; itching; or decreased urination. Hydrocodone and ibuprofen is habit forming. Dependence may develop if it is taken for a prolonged period of time and withdrawal effects may occur if it is stopped suddenly after prolonged treatment. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. Notes Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Drug Interactions Before taking Vicoprofen, tell your doctor if you are taking any of the following medicines: another nonsteroidal anti-inflammatory drug (NSAID) such as ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox), diclofenac (Voltaren, Cataflam), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin); aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate, and magnesium salicylate; a diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide (Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone), and amiloride (Midamor); an anticoagulant such as warfarin (Coumadin); or lithium (Eskalith, Lithobid, others). You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. Drowsiness or dizziness caused by Vicoprofen may be increased by the effects of other drugs that cause drowsiness including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, muscle relaxants, and many others. Tell your doctor about all medicines that you are taking and do not take any medicine without first talking to your doctor. Drugs other than those listed here may also interact with Vicoprofen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products. Missed Dose Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking your next dose. Storage Store Vicoprofen at room temperature away from moisture and heat. Keep this and all medications out of the reach of children.
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